Rate-dependent AV delay optimization in cardiac resynchronization therapy.

Primary results from the SmartDelay determined AV optimization: a comparison to other AV delay methods used in cardiac resynchronization therapy (SMART-AV) trial: a randomized trial comparing empirical, echocardiography-guided, and algorithmic atrioventricular delay programming in cardiac resynchronization therapy.

BACKGROUND one variable that may influence cardiac resynchronization therapy response is the programmed atrioventricular (AV) delay. The SmartDelay determined av optimization: a comparison to other AV delay methods used in cardiac resynchronization therapy (SMART-AV) trial prospectively randomized patients to a fixed empirical AV delay (120 milliseconds), echocardiographically optimized AV dela...

Echocardiographic optimization of the atrioventricular and interventricular intervals during cardiac resynchronization.

An optimized atrioventricular (AV) interval can maximize the benefits of cardiac resynchronization therapy (CRT). If programmed poorly, it may curtail beneficial effects of CRT. AV optimization will not convert non-responder to responder, but may convert under-responder to improved status. There are many echocardiographic techniques for AV optimization but there is no universally accepted gold ...

Definition of the Optimal Atrioventricular Delay by Simultaneous Measurement of Electrocardiographic and Doppler Echocardiographic Parameters

In atrioventricular (AV) block patients, AV synchrony can be restored by implanting DDD pacing systems if an individual optimization of the pacemaker AV delay is performed. If the latter is neglected and the AV delay is left at nominal settings, adverse hemodynamic effects may develop. Therefore, several methods were proposed to calculate or to estimate the individual hemodynamically optimal le...

Cardiac resynchronization therapy during rest and exercise: comparison of two optimization methods

AIMS Optimal exercise programming of cardiac resynchronization therapy (CRT) devices is unknown. We aimed to: (i) investigate variations in optimal atrioventricular (AV) and interventricular (VV) delays from rest to exercise, assessed by both echocardiography and an automated intracardiac electrogram (IEGM) method; (ii) evaluate the acute haemodynamic impact of CRT optimization performed during...

Randomized prospective trial of atrioventricular delay programming for cardiac resynchronization therapy.

OBJECTIVES The purpose of this study was to determine if AV delay optimization with continuous-wave Doppler aortic velocity-time integral (VTI) is clinically superior to an empiric program in patients treated with cardiac resynchronization therapy (CRT) for severe heart failure. BACKGROUND The impact of AV delay programming on clinical outcomes associated with CRT is unknown. METHODS A rand...

Primary Results From the SmartDelay Determined AV Optimization: A Comparison to Other AV Delay Methods Used in Cardiac Resynchronization Therapy